How large is XBI and what does it cost to hold?

XBI currently manages $8.06B in assets. The annual expense ratio (TER) is 0.35%, deducted directly from fund assets. Portfolio turnover stands at 43%, reflecting how frequently holdings are replaced within a year. Lower expense ratios compound favorably over time – a 0.08% TER on a 10-year holding period adds up to meaningfully less drag than a 0.5% fund.

What are the largest holdings in XBI?

XBI allocates 96.1% of its portfolio to Healthcare. The three largest holdings are MRNA (2.3%), ROIV (1.8%), ACLX (1.7%). Concentration in the top holdings means single-name events in these positions can have an outsized effect on the ETF's price.

Does XBI pay dividends or distributions?

XBI currently distributes a yield of -0.13%. ETF distributions are typically passed through from dividends and interest generated by the underlying holdings. The actual payout frequency depends on the fund structure – most sector ETFs distribute quarterly.

What is XBI's historical performance?

Reported performance for XBI: year-to-date 4.46%, 3-year cumulative 18.85%, 5-year cumulative -1.31%. Past performance is not indicative of future results. Returns reflect price changes only and may differ from total return figures that include distributions.

What is the current trend signal for XBI?

As of the most recent session, XBI closed at $150.23. The swing trend is negative with ADX at 39.2 (strong trend strength). Momentum is bearish and has been running for 22 trading days. A Golden Cross is in place. Price has been compressing for 6 consecutive sessions – a breakout setup is building. All data is updated once per trading day after the US market closes.

When was the last Trendchange signal for XBI?

The most recent Trendchange signal for XBI fired on 15.06.26 at $136.40. The position has been open for 48 trading days. Performance after 10 days: +16.06%. The system's historical edge across 71 tracked signals is +4.99%. Trendchange signals are based on proprietary moving average crossover logic applied to end-of-day price data.

XBI – State Street SPDR S&P Biotech ETF

ETF

Health | Inception: 2006-01-31

Quick Stats

Trend Signal

$150.23

Last Close

Official EOD price – basis for all calculations

▼ Short

Swing Trend

Moving average structure confirms downtrend – bears in control

+4.99%

Signal Edge

Slim positive edge across 1 signals – treat with caution

39.2

Trend Strength (ADX)

Strong trend – directional signals reliable

Options Signals

27%

IV-Rank (52w)

IV in normal range – no clear vol edge

72% / 28%

Call / Put Flow

Bullish positioning – call premium dominates options flow

Last Trendchange Signal

15.06.26

Date

Signal entry date

$136.40

Entry Price

Closing price at signal date

48d

Days Held

Trading days since signal

+16.06%

+10d

Return after 10 trading days

+13.97%

+20d

Return after 20 trading days

+14.53%

+30d

Return after 30 trading days

+14.53%

+60d

Return after 60 trading days

Trend Overview

Volatility Compression – Wait for Breakout Composite Score: 0 / 7

XBI has been in a volatility compression for 6 consecutive sessions. Price is coiling and the range is contracting. This kind of structure typically resolves with an expansion in one direction – and the underlying trend bias remains negative, which tilts the probability toward a downside continuation. The key question is not if the move happens, but when and which way.

What to watch

This is a waiting game. Define the breakout level in advance, set alerts at the range boundaries, and let the market make the first move.

XBI Price Chart

Technical Trend Analysis

As of 07.10.2026 · Close: $150.23 · ATR14: $2.86

Volatility Compression – Wait for Breakout Composite Score: 0 / 7

What to watch

This is a waiting game. Define the breakout level in advance, set alerts at the range boundaries, and let the market make the first move.

Indicator	Signal	Detail
Swing Trend	▼ Short	Primary directional bias
Momentum	▼ Down · -22d	Strength: -0.26 – Fading
Trend Strength (ADX)	39.2 – Strong	ADX38: 8.9
Volatility (HV30)	25.8% – Calm	HV90: 30.6% \| HV180: 30.0%
Vola Compression	6 days active	Potential breakout building
MA Structure	Golden Cross ✓	Stack: Mostly aligned (2/3)
EMA21 Distance	-1.32 ATR ↑	EMA21: $154.41
GD200 Extension	2.7 ATR – Normal	GD20: -1.3 \| GD50: -1.8 \| GD100: -0.2

🟡 Downside Momentum Easing

Downward momentum has run -22 days but strength is decreasing (-0.26). The move may be exhausting.

💪 Trend Strength – ADX14: 39.2 (Strong)

A strong and well-defined trend. ADX38: 8.9. Trend-following has clear edge here.

🔻 Volatility Calm

HV30: 25.8% | HV90: 30.6% | HV180: 30.0%. Short-term vol is below its 90-day average. Calmer conditions favour tighter setups.

🗜️ Volatility Compression – 6 Days Active

Price has been compressing for 6 sessions. The longer the compression, the more powerful the potential breakout.

⭐ Golden Cross – Long-term Bullish

Golden Cross in place. GD50 $158.18 above GD200 $139.30 by 13.55%. Long-term structure is bullish. MA stack: Mostly aligned (2/3).

📈 EMA21 – Trend Accelerating

Price is pulling away from the EMA21 ($154.41) with -1.32 ATR distance and growing.

📐 Key Price Levels & ATR Distance

GD20: $155.88 (-1.3 ATR) | GD50: $158.18 (-1.8 ATR) | GD100: $151.19 (-0.2 ATR) | GD200: $139.30 (2.7 ATR). ATR14: $2.86.

Monthly Performance History

Year	Jan	Feb	Mar	Apr	May	Jun	Jul	Aug	Sep	Oct	Nov	Dec	Total
2010	1.43	0.78	1.16	-0.15	-11.78	-3.09	8.50	-6.24	10.30	0.42	0.37	5.03	15.77
2011	-3.27	0.70	7.36	9.78	1.56	-0.30	-3.79	-10.07	-3.68	16.65	2.34	1.09	3.90
2012	15.60	-2.57	3.65	0.08	-0.88	13.01	-2.34	1.50	3.06	-10.54	4.12	-0.04	32.94
2013	4.22	-2.20	5.17	7.41	7.71	-4.90	12.74	-4.17	5.82	-9.72	9.08	-0.71	42.98
2014	14.79	14.21	-12.57	-11.51	1.50	18.36	-6.69	11.64	-2.53	11.36	4.84	7.00	44.25
2015	5.97	9.23	3.79	-6.54	11.73	5.71	2.50	-12.83	-13.30	6.73	1.85	-2.44	12.39
2016	-25.47	-6.00	3.01	1.45	5.55	-6.96	11.20	-5.47	9.91	-15.15	10.27	-3.15	-12.49
2017	8.92	8.09	-2.95	T 4.58	-6.12	T 11.09	0.34	T 8.75	2.35	-4.92	0.87	T 1.78	42.81
2018	7.06	-3.46	T -1.93	3.73	T 7.68	-1.45	-1.04	T 5.00	-4.06	-16.37	-2.50	-15.21	-17.56
2019	T 14.75	6.13	-1.38	-5.78	-5.02	T 9.14	-2.91	-6.44	-3.06	T 9.36	11.95	3.02	30.56
2020	-5.88	T -2.13	-16.47	T 27.49	14.01	7.54	-2.80	-1.86	T 1.78	-0.05	18.13	6.02	49.00
2021	8.46	-7.28	-10.49	-0.30	-5.10	T 7.08	-10.89	T 7.19	-6.94	-1.08	T -10.28	-0.15	-20.55
2022	-19.06	-5.38	T 0.89	-20.83	-10.42	T 9.97	6.00	5.31	-7.24	2.72	0.96	-0.11	-28.10
2023	T 9.05	-7.67	-8.30	T 4.07	2.81	-2.21	1.63	-4.92	-10.00	-6.26	T 11.72	14.72	10.11
2024	-3.10	10.62	-6.54	-9.83	T 2.06	1.41	6.47	2.62	0.14	-0.96	T 0.35	T -9.31	-0.19
2025	1.25	T -2.96	-5.26	T 6.13	-4.01	2.08	3.11	4.56	7.88	11.16	12.11	1.74	33.21
2026	2.66	T 0.02	0.93	T 2.16	T 4.81	T 18.43	-6.09	10.31	-3.50	-2.77			23.63

T A T badge marks a Trendchange signal in that month. Hover for entry price.

XBI - Trendchange Chart

Trendchange Signal History

The last 10 Trendchange signals for XBI:

Date	Entry Price	Days Held	+10d	+20d	+30d	+60d
15.06.26	$136.40	48d	+16.06%	+13.97%	+14.53%	+14.53%
29.05.26	$136.69	1d	-2.25%	+0%	+0%	+0%
07.04.26	$128.85	21d	+6.94%	+1.79%	+1.79%	+0%
24.02.26	$129.16	3d	-2.02%	-2.02%	-2.02%	+0%
29.04.25	$81.88	12d	-6.7%	-6.7%	-6.7%	-6.7%
05.02.25	$94.70	4d	-5.97%	-5.97%	-5.97%	-5.97%
06.12.24	$99.14	4d	-2.19%	-2.19%	-2.19%	-2.19%
06.11.24	$102.44	9d	-5.35%	-5.35%	-5.35%	+0%
14.05.24	$90.78	8d	-1.82%	-1.82%	-1.82%	-1.82%
17.11.23	$72.66	54d	+7.12%	+17.97%	+24.18%	+21.58%

Signal Statistics - Historical Edge

Calculated edge for XBI: 4.99%

Range	N	10d	20d	30d	60d	Signal
15-20%	1	+16.06%	+13.97%	+14.53%	+14.53%	Hold
10-15%	2	+12.04%	+17.62%	+18.27%	+18.97%	Hold
7-10%	3	+8.01%	+10.71%	+12.86%	+12%	Hold
5-7%	9	+6.02%	+7.37%	+9.17%	+9.24%	Hold
3-5%	8	+3.92%	+4.18%	+5.37%	+5.25%	Close
1-3%	9	+1.68%	+2.72%	+3.39%	+4.21%	Hold
0-1%	3	+0.55%	+2.65%	-0.3%	-0.3%	Close
-1-0%	6	-0.43%	-0.54%	-0.47%	-0.01%	Neg
-3-1%	18	-2.02%	-0.54%	-0.74%	-0.04%	Neg
-5-3%	6	-3.89%	-4.38%	-3.63%	-3.63%	Neg
-7-5%	6	-5.99%	-6.77%	-6.77%	-4.17%	Neg

Exit Rules: Stoploss: -10% | Close if below 1% after 10 days

Signal data as of October 7, 2026

MEDIUM ALERT ● Neutral Strength: 5.5

Options Metrics

IV-Rank (52w)

27%

IV is in its normal historical range – no structural vol edge in either direction.

Call / Put Flow

72% / 28%

More than 60% of options premium is flowing into calls. This indicates net bullish positioning by market participants.

GEX (Mio.)

-10,689,290.3

Negative GEX: market makers are short gamma. They sell dips and buy rallies, which amplifies moves and increases volatility.

GEX Flip Strike

$146.00 · 2.8%

The GEX flip strike is the price level where dealer gamma exposure shifts from positive to negative. A break through this level often accelerates the move.

Max Pain

$150.00 · 0.2%

Max Pain is the price at which the most options contracts expire worthless. As expiration approaches, price often gravitates toward this level due to dealer hedging flows.

Spot Price

$150.23

Last traded price at signal calculation time

Gamma Exposure Timeline

Key GEX levels, Max Pain, and unusual activity across weekly and monthly expirations, plotted around the current spot price.

XBI GEX timeline showing put/call gamma pins, max pain and flip strike

Key GEX levels, Max Pain, Anchor, Ceiling and unusual activity across 14-30 DTE, plotted around the current spot price.

Put and call pins mark strikes where dealer gamma exposure concentrates. The GEX flip strike is where dealer hedging shifts from stabilizing (positive gamma) to amplifying (negative gamma) price moves. Max Pain is the strike where the most options expire worthless. Dashed markers flag unusual options activity. Learn how to use these signals in our options strategy guides →

View full options flow data and historical signals on the Options Flow Analysis Overview →

About State Street SPDR S&P Biotech ETF

In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a sampling strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology segment of the S&P Total Market Index ("S&P TMI").

Fund Overview

Metric	Value
Assets under Management	$8.06 B
Expense Ratio	0.35%
Dividend Yield	-0.13%
Portfolio Turnover	43%
YTD Return	4.46%
3-Year Return	18.85%
5-Year Return	-1.31%

Sector Allocation

Sector	Weight
Healthcare	96.1%

Top 10 Holdings

Symbol	Company	Weight
MRNA	MODERNA INC	2.31%
ROIV	ROIVANT SCIENCES LTD ORDINARY SHARES	1.79%
ACLX	ARCELLX INC	1.67%
PCVX	VAXCYTE INC ORDINARY SHARES	1.63%
RVMD	REVOLUTION MEDICINES INC ORDINARY SHARES	1.55%
FOLD	AMICUS THERAPEUTICS INC	1.49%
GILD	GILEAD SCIENCES INC	1.49%
AMGN	AMGEN INC	1.45%
PRAX	n/a	1.45%
CELC	CELCUITY INC	1.4%

Frequently Asked Questions – State Street SPDR S&P Biotech ETF (XBI)

Disclaimer: All trade history on this page reflects the author's personal trading activity only. This is not financial advice. Past performance is not indicative of future results. See our full Disclaimer.